Ray Barrett

Chairman

Ray founded Biomedical Systems in 1975. He is a visionary who continues to anticipate the changing needs of healthcare related issues and responds with a do-it-now philosophy. Under his leadership, Biomedical Systems has grown into a global organization offering clinical trial services, physician/cardiology services, and medical products with offices in North America, Europe and Asia serving several different healthcare markets.

A consummate entrepreneur, Ray founded Landshire food systems, a manufacturer and distributor of packaged goods in 1959. He developed it into a multimillion dollar enterprise with franchises in 37 cities throughout the United States before selling it to the Southland Corporation (parent company of 7-11) in 1977. He is probably one of only a handful of people in the United States to have built – from scratch – two highly successful, unrelated international companies in Biomedical Systems and Landshire Food Systems. Ray is an inventor and holder of several patents, including products developed for Biomedical Systems. He has served on 15 corporate and civic boards in the Greater Saint Louis area including two law enforcement organizations: The Medal of Valor and The Backstoppers, Inc.

Ray is the founder of the Minority Economic Development Corporation (MEDC), the first organization of its kind designed to identify qualified minority individuals and facilitate their participation in “mainstream America” by pairing them with successful franchisors. In 1989, Ray formed Hand-Up (Helping a Neighbor Develop Unlimited Possibilities), a volunteer organization which helps families avoid falling into the cycle of poverty through financial assistance and counseling. Ray pioneered several additional assistance programs, including a program to provide hundreds of thousands of meals to disadvantaged children with the cooperation of the St. Louis Mayor’s Council on Youth, the United Auto Workers, and U.S. Department of Agriculture. In 2011, Ray’s fondness for children was shown again as he built the playground for the Guardian Angel Settlement Association, an organization headed by Rev. Jerry Morales that has been serving the needs of children and teens since 1859. For the 2011-2012 school year, Ray donated 26 electrocardiograph (ECG) machines to the St. Louis Public School Systems. These machines will be used by students to improve their knowledge of the cardiovascular system as well as gain important training that will help them in the future as they apply for healthcare related positions. This is the first year of an ongoing program with the school district.

Ray, a veteran of the Korean War, served in the United States Army in Korea from 1953 thru 1955. Upon his return he earned a Bachelor of Arts in Business Administration from St. Louis University. He continued his graduate work at Washington University in St. Louis. Ray is a 1960 business school graduate of SLU who received the University’s “Distinguished Alumnus of the Year” award in 1989. Throughout St. Louis, he is widely known as an “Entrepreneurs’ Entrepreneur.” He was inducted into the inaugural class of the St. Louis University Entrepreneurial Alumni Hall of Fame in 2007. Selected from over 100 distinguished nominees, Ray was honored in the Hi-Tech Category as an “Individual who has displayed the characteristics of entrepreneurial leadership as a founder, owner or top manager of a firm identified as a high-technology business.”

Tim Barrett

Chief Executive Officer

In 1980, Tim Barrett received a Bachelor of Arts and a Business Administration Certificate from St. Louis University where he later received his Juris Doctorate in 1983. Prior to joining Biomedical Systems, he worked as an attorney for a St. Louis based law firm.

Tim began his career at Biomedical Systems in 1987 as Vice President, Corporate Development/General Counsel. In this capacity, he was involved in several corporate acquisitions as well as the sale of a division which provided substantial capital to fund the expansion of the company’s current operations. In 1991, Tim took over management of the company’s Centralized ECG Division. Subsequently, the division grew through its provision of clinical trial services and centralized data to the pharmaceutical industry. In his current capacity as Chief Executive Officer, Tim Barrett oversees operations in the United States, Europe, and Asia.

In addition to his professional responsibilities, Tim devotes his time and resources to several civic and charitable organizations in various capacities including the Productive Living Board for St. Louis County Citizens with Developmental Disabilities, De Smet Jesuit High School, and Villa Duchene/Oak Hill School. He also serves on the Board of Trustees of Triad Bank.

Dan Barrett

Chief Operating Officer

Dan Barrett earned his Bachelor of Arts in Economics and Business Administration from Vanderbilt University in 1983 and a Juris Doctorate from St. Louis University in 1986. Prior to joining Biomedical Systems, he gained experience as a private practice attorney and as legal counsel for a major brokerage firm based in the United States. Dan accrued essential strategic planning and development skills through these experiences which have contributed to Biomedical Systems on-going success since joining the board of directors in 1989. In Dan’s present position as Chief Operating Officer of Biomedical Systems, he oversees corporate operations, legal matters, and acquisitions.

Dan has served on numerous charitable, private, and local governmental boards in the St. Louis area including several which serve the youth of the community.

Patrick Barrett

Chief Marketing Officer

Having completed his undergraduate degree in Business Administration at Southern Methodist University, Patrick Barrett earned his Master of Business Administration degree from Washington University in St. Louis. After joining Biomedical Systems, Patrick managed the Wound Care Products Division which marketed the patented pressure relief device, the Heeler®, and headed up the Women’s Health Services Division which specialized in providing home obstetrical services throughout the country. In his current capacity as the Chief Marketing Officer for Biomedical Systems, Patrick is responsible for defining the strategic planning and initiatives of the company to position it for long-term growth.

Patrick serves on many civic and business organizations, including the Missouri Governor’s Advisory Council on Aging, the Kilo Diabetes Foundation Board, the Action for Autism Board, and the St. Louis Bank Advisory Board.

Amy Stewart

Human Resources Director

Amy Stewart began her career as a recruiter in 1996 quickly progressing into other arenas of human resource management including performance improvement and process efficiency. Her analytical and problem solving skills drove operational change and process improvement to increase productivity and company profits in her former position at a customer management solutions firm. In 2010, Amy brought her fourteen years experience to Biomedical Systems as the Human Resource Manager. Her training in strategic planning, performance management, recruiting leadership, employee relations, and employment law in addition to FMLA/LOA certification makes Amy an asset to the company. Dedication to personal service and a commitment to corporate achievement propelled Amy into her current position as Human Resources Director where she has worked strategically with executive leadership to facilitate Biomedical Systems’ global success.

Jayuni Buescher

Chief Financial Officer

Jayuni Buescher obtained her C.P.A. license after graduating magna cum laude from the University of Missouri-Columbia in 1990. In the fourteen years before her arrival at Biomedical Systems, she worked as a senior financial analyst for two preeminent healthcare systems. As the manager of accounting, Jayuni worked closely with the former CFO, Tom Modglin, in her nine year tenure at Biomedical Systems. Her financial acumen and mastery of the company’s business model makes Jayuni uniquely qualified for her new position as Chief Financial Officer.

Jim Ott

Chief Technology Officer

Jim Ott received his Bachelor of Science in Biomedical Engineering at Marquette University in 1989. In 1991, he earned a Master of Science in Biomedical Engineering at Marquette University joining Biomedical Systems the following year. In his twenty year tenure at Biomedical Systems, Jim has held senior leadership positions facilitating the development of diagnostic cardiology software and network and internet solutions for medical data transfer. His instrumental work culminated in the issuance of a patent for the TruVue® Wireless ECG Monitoring system. In his current position as Chief Technology Officer, Jim leads the efforts to identify best in class solutions for technology needs across all facets of the industry.

Joseph Pierro, MD

Chief Medical Officer - North America

Dr. Joseph Pierro brings over 25 years of imaging expertise in the field of radiology and more than 20 years of clinical trial research and development experience to Biomedical Systems. He has served in global senior level positions within the pharmaceutical industry and as a medical reviewer at the FDA Center for Drug Evaluation and Research. Dr. Pierro has been instrumental in numerous submissions to regulatory agencies offering substantial experience in scientific review and medical writing of clinical development strategy, clinical protocol development, and clinical study reports. In addition to imaging, Dr. Pierro provides broad expertise in safety, medical monitoring, pharmacokinetics, pharmacodynamics, biostatistics, and clinical safety reporting. His thorough understanding of regulatory submission requirements and outstanding track record of success with regulatory approvals and responses to regulatory authorities make Dr. Pierro an asset to Biomedical Systems’ Scientific Affairs team. He has contributed to numerous scientific publications in peer reviewed journals and authored a manual of radiology. Dr. Pierro received his medical degree at the State University of New York at Buffalo School of Medicine and completed residency training in diagnostic radiology at Northeastern Ohio’s Integrated Residency program in Youngstown, Ohio.

Pierre Maison-Blanche, MD

Chief Medical Officer

For the past thirty years, Dr. Maison-Blanche has performed angiography and clinical research in the cardiovascular therapeutic area in the Cardiology Department at Lariboisière Hospital where his clinical specialty is non-invasive cardiac electrophysiology. Dr. Maison-Blanche organized the first digital ECG Laboratory at Lariboisière Hospital under the leadership of Dr. Philippe Coumel. In 1998, he established the Centralized ECG Services Department for MDS Pharma Services in Paris, France and chaired the MDS ECG Advisory Board from 2002 – 2006. Dr. Maison-Blanche has participated in several End of Phase II meetings with the Food and Drug Administration (FDA) as well as in Advisory Boards as an active member. He is currently a member and the Chairman of Data Monitoring Committees for on-going, multicenter clinical trials. In addition to his duties as Biomedical Systems’ Chief Medical Officer, Dr. Maison-Blanche serves as a Consultant for Assistance Publique des Hôpitaux de Paris. He earned his medical degree in 1981 from the University of Paris and specialized in Cardiology at Lariboisière Hospital. Dr. Maison-Blanche is a highly sought after speaker and has been published in leading journals around the world. He is a member of numerous professional societies and boards including the International Society for Holter and Noninvasive Electrocardiology.

Timothy Callahan, PhD

Chief Scientific Officer

Dr. Timothy Callahan has served as Biomedical Systems’ Chief Scientific Officer since 2001 and brings over 25 years of clinical research expertise to the position including conducting research in Silent Myocardial Ischemia at the National Institutes of Health in Bethesda, Maryland. An expert in diagnostic testing, Dr. Callahan co-authored 2 patents in QT interval analysis and a patent in dynamical systems modeling of ECG data. He has authored many abstracts and publications as well as serving as the moderator for the past three FDA QT-IRT – ECG Core Lab meetings. Dr. Callahan received his Ph.D. from Capella University in Interdisciplinary Studies with a concentration in Research Methodology. He is a frequent speaker at Pharmaceutical Industry functions and sits on a number of advisory boards for peer reviewed publications.

Jay Winship, MD, FACP

Senior Medical Advisor

Dr. Winship provides sponsor organizations with expert advice and consultation from protocol design to NDA submission. With over 25 years of clinical trial experience, Dr. Winship has held senior medical research positions with Omnicare, Light Science Oncology, IDUN Pharmaceuticals and Hoechst Marion Russell. Prior to working in the clinical trial field, Dr. Winship was a practicing physician in Missoula, Montana with a large practice in Internal Medicine and Infectious Disease serving both adult and pediatric populations. Dr. Winship is a graduate of Northwestern University Medical School and is Board Certified in Internal Medicine, Infectious Disease, Geriatrics, Medical Microbiology, and Infection Control. He has served on the faculty of numerous colleges and universities, is a member of several professional societies and has been an editorial reviewer and writer for many peer reviewed medical journals.

Yukiharu Yamaguchi, PhD

Senior Clinical Research Advisor

Dr. Yamaguchi has over 30 years of research and development experience at Japanese and global pharmaceutical companies including Pfizer. He is a member of several professional organizations including The Japanese Pharmacological Society, The Biometric Society of Japan, and The Japanese Society of Magnetic Resonance in Medicine. Dr. Yamaguchi earned his B.Sc. from Tokyo University in the Department of Pure and Applied Sciences and his Ph.D. from the University of London, St. George's Hospital Medical School. He is a well known speaker at pharmaceutical industry events as well as a frequent contributor to peer reviewed publications.

Luc Dekie, PhD

Director of Scientific Affairs, Europe

Dr. Dekie has worked in the clinical trial field for the past ten years with Biomedical Systems and Bio Analytic Research Corporation (BARC). His scientific expertise in addition to his ability to speak English, French, and Dutch make him a valuable member of the Scientific Affairs team. Working out of the European headquarters in Brussels, Dr. Dekie helps to provide assistance to pharmaceutical and medical device sponsors in the field of study design and execution, statistical analysis, and report writing. He holds a PhD in Sciences and a Master in Biomedical and Clinical Engineering Techniques from the University of Gent. Dr. Dekie is well published and holds a patent for Synthetic Polyamino acid complexes for delivery of nucleic acids to target cells.